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The Methylcobalamin version of B12 helps reduce homocysteine concentration by converting homocysteine to methionine through a methylation process

A deficiency of Vitamin B12 can lead to advanced anemia where the red cells are fewer in number but are larger than normal (macrocytic)

- when there is risk of torsades de pointes, for example in patients with prolonged QT, concomitant administration of other medications that produce torsades de pointes (amiodarone, quinidine, bepridil, IV erythromycin, halofrantine, pentamidine, sparfloxacin, sultopride, vincamine, betrilio, disopyramide, sotalol, etc)

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Cold compresses and ice packs can help to alleviate swelling and may be used during the first two days after the procedure

While there is no exact definition for B12 levels, a normal B12 serum test level is considered around 300-900pg/mL, while deficiency is less than 200 pg/mL